Lolla Brigida and Janet Shyster stumble into the Shyster & Shyster tax return preparation partnership. Accompanied by a hard-nosed female dwarf debt collector, a perpetual student intern with ADHD and a romantic interest who never gives up, the women take a humorous journey from hardly making it to losing it all to tax bracket madness.

To save their profits, Lolla and Janet turn the tax business into a church that mixes religious beliefs at will. Add a married Mother Superior, four children sold as tax deductions and an exorcism, and the women experience the miracle of true friendship and monetary success.